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Other HSC mediated factors such as low oxygen angiogenic or
2019-04-29

Other HSC-mediated factors, such as low oxygen [17], angiogenic [18], or additional secreted factors can also control dormancy. Shiozawa et al. [19] reported that growth arrest specific-6 (GAS6), a ligand of TYRO3, AXL, and MER tyrosine kinase receptors produced by osteoblasts in the HSC niche, supp
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Cell adhesion to extracellular matrix requires the interacti
2019-04-29

Cell adhesion to extracellular matrix requires the interaction of different molecules like selectins, cadherins and integrins [21]. Especially αvβ3 integrin has been proposed to mediate the adhesion of malignant cells in different entities such as multiple myeloma and breast cancer [22,23]. Upon exp
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Electrical storms in patients during the
2019-04-29

Electrical storms in patients during the early phase of an MI are occasionally initiated by abnormal automaticity originating from damaged partially depolarized myocytes or Purkinje fibers [11]. Several studies have reported that ampk inhibitor RFCA targeting Purkinje potentials in the infarction b
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The methods used for this purpose are substantially the anal
2019-04-29

The methods used for this purpose are, substantially, the analyses of atrial potentials, evoked atrial potentials [10], and ventricular rhythm in cases of stable spontaneous AV conduction [11]. Materials and methods Results Discussion This is the first report on the current ACAP Confirm® r
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With one in three women affected by gender based violence
2019-04-29

With one in three women affected by gender-based violence, support services remain essential and should not be supplanted by prevention of perpetration. Instead, national and international gender-based violence responses should be simultaneously committed to perpetration prevention and accountabilit
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Se puede decir que a pesar de
2019-04-29

Se puede decir que, kinesin 5 pesar de la dispersión espacial y la heterogeneidad lingüística que los caracteriza, los pueblos englobados bajo el apelativo Gente del centro conforman una misma sociedad, debido a que comparten un mismo complejo ceremonial organizado en torno al consumo e intercambio
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Un aspecto significativo que debe
2019-04-29

Un aspecto significativo que debe tenerse igualmente en cuenta para estos mismos años es que, en 1584, el arzobispo Moya de Contreras tuvo pretensiones de reactivar el programa secularizador en la ciudad de México, hecho que, tras la celebración del autoritativo iii Concilio Provincial Mexicano en 1
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La definici n de los distintos
2019-04-29

La definición de los distintos grupos se caracterizó, entonces, herpes simplex virus 1 través de un mote o sobrenombre, utilizado desde la comunicación codificada hasta la jerga revolucionaria que incluía el gesto de denigrar a las otras organizaciones por la postura que tenían respecto a la guerra.
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O modelo alvo de preocupa es de Homi Bhaba
2019-04-29

O modelo é alvo de preocupações de Homi Bhaba, que o enxerga como uma oposição à diferença cultural. A diversidade funcionaria como contenção da diferença, executada por meio do controle e localização da diferença nos circuitos dominantes. A administração dessa diversidade se dá mediante haspin inhi
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In patients with systolic heart failure
2019-04-28

In patients with systolic heart failure and a wide QRS complex, cardiac resynchronisation therapy (CRT) using left ventricular (LV) pacing has been shown to enhance survival, reduce heart failure hospitalisation and enhance exercise capacity in patients with all ionomycin of heart failure. The pati
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El poema describe un universo en continua
2019-04-28

El poema describe un universo en continua ruina que da la sensación en ocasiones de revivir la imaginería nerudiana de Residencia en la tierra. Flota en el texto un sentimiento de ocaso, potenciado por el léxico de la hecatombe y del tumulto, cuyas figuras más evidentes son “estallan”, “pólvora”, “e
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Long marginalised as a disorder confined to
2019-04-28

Long marginalised as a disorder confined to specific racial groups, sickle-cell disease is now assuming its rightful place as a major global public health problem. Most patients in the Americas, the Caribbean, and much of Europe have been of one racial group, which led to the common misconception th
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If a structurally normal patient with polymorphic
2019-04-28

If a structurally normal patient with polymorphic VT/VF storm has a completely normal baseline ECG, the possible diagnosis includes CPVT and idiopathic VF. CPVT is an inherited disorder of intracellular Ca2+ handling, which can cause polymorphic VT/VF storms [10]. Abnormal SR Ca2+ release from defec
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Initial radiographs demonstrated an aggressive
2019-04-28

Initial radiographs demonstrated an aggressive lesion in the medial condyle of the distal right femur (Figs. 1A and B). CT obtained to characterize matrix showed an aggressive lesion with a focus of dense linear matrix (Fig. 2) with intervening lucent areas. The lesion was felt to be indeterminate a
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An incisional biopsy was undertaken Peri operative examinati
2019-04-28

An incisional biopsy was undertaken. Peri-operative examination of the lesion revealed an expansile tumor mass brownish in color with focal whitish areas (Fig. 3). The lesion could be delineated from the surrounding cortical bone, and surrounding soft tissues. Histopathologically the biopsy material
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