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The authors of the NCCN non small
2019-06-06
The authors of the NCCN non-small cell lung cancer guidelines provide the most guidance about radiotherapy dosing for painful bone metastases of any of the primary sites evaluated [39]. Bone metastases due to non-small cell lung cancer are separated into those “with soft tissue mass” versus those “w
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The requirements for establishing this arrhythmia are as fol
2019-06-06
The requirements for establishing this arrhythmia are as follows: (1) a slow pathway (or maybe a fast pathway) should not have retrograde conduction; and (2) the refractory SEA0400 of the distal common pathway must be shorter than the difference in the conduction times over the fast and slow pathwa
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A substantial body of evidence linking inflammation
2019-06-05
A substantial body of evidence linking inflammation to the pathophysiology of a broad spectrum of cardiovascular diseases, including coronary artery disease, diabetes mellitus, and hypertension, has been developed [8–11]. Similarly, the hypothesis that inflammatory processes are involved in the path
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br Materials methods br Results br Discussion The
2019-06-05
Materials-methods Results Discussion The general statement that can be concluded from the studies comparing the utility of 18F–NaF PET or PET/CT with 99mTc- MDP whole body bone scintigraphy is that 18F–NaF PET/CT generally has a higher sensitivity and specificity than bone scan. Higher upta
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Hill and colleagues estimate that globally about
2019-06-01
Hill and colleagues\' estimate that, globally, about 1·5 million (95% CI 1·2–1·8) children aged 5–14 years died in 2010. This finding is somewhat higher than the total estimated by the UN of 1·3 million, although the UN estimate is within the investigators\' CI. However, their estimate is 87% higher
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tranylcypromine En otra rbita George Y dice
2019-06-01
En otra órbita, George Yúdice establece una doble genealogía refiriéndose al testimonio que se realiza tranylcypromine partir de la información que proporciona un sujeto subalterno a un escritor o a un intelectual. Yúdice se refiere aquí a la pedagogía de los oprimidos de Paulo Freire y a la Teolog
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br The UN high level Summit for Refugees
2019-06-01
The 2016 UN high-level Summit for Refugees and Migrants in New York (NY, USA) provided a historic opportunity to engage world leaders in responding to the health dimensions of mass migration. Despite the magnitude of the phenomenon and its potential for changing global as well as national health p
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More recently primary tumor driven generation of
2019-06-01
More recently, primary tumor driven generation of a bone pre-metastatic niche was observed in a mouse model of estrogen receptor-negative breast cancer metastasis. Specifically, lysyl oxidase (LOX) secreted into the circulation from hypoxic primary breast tumors disrupted bone homeostasis, thereby i
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Heat shock facilitates the folding of
2019-06-01
Heat shock facilitates the folding of various proteins as mediated by the HSP family and can stabilize mutant proteins. HS has been reported to facilitate maturation of WT-HERG as well as mutant HERG by activating the HSF family [15]. HSF-1, 2, and 4 were reported to be expressed in humans. HSF-1 is
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palmitic acid The increasing burden of NCDs poses an
2019-06-01
The increasing burden of NCDs poses an enormous threat to populations and health systems across the globe. The Sustainable Development Goals represent an important opportunity to integrate efforts to reduce the burden of NCDs and promote sustainable development. The recent identification of NCDs as
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Although Afnan Holmes and colleagues report covers
2019-06-01
Although Afnan-Holmes and colleagues\' report covers substantial ground, several issues remain unexamined. For example, why have facility delivery rates in the country stagnated at roughly 50% over the past decade? Although enhancement of women\'s agency in making health-care decisions is necessary,
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thymidylate synthase Por supuesto para que el
2019-06-01
Por supuesto, para que el reconocimiento de los campesinos se constituya como nacional es necesaria una relación de poder bastante poco estudiada, en la que sectores oligárquicos podrían representar a los campesinos. Esta articulación sería desestabilizada de vez en cuando, como por ejemplo cuando S
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PI103 La embajada argentina en Guatemala consideraba
2019-06-01
La embajada argentina en Guatemala consideraba que, PI103 diferencia de El Salvador, el ejército guatemalteco y las fuerzas armadas en general mantenían una cohesión firme contra el comunismo. Esta certeza calmaba más las ansiedades que las cordiales relaciones mantenidas con el anticomunista Mario
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The ability of tumors to progress to more malignant phenotyp
2019-05-31
The ability of tumors to progress to more malignant phenotypes depends on tumor microenvironment. Blood capillaries, made up of endothelial cells, are usually static under physiological conditions but are induced to proliferate by direct exposure to angiogenic factors, for instance, vascular endothe
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br Tuberculosis remains a global emergency and
2019-05-31
Tuberculosis remains a global emergency and continues to present major public health challenges worldwide. The actual global burden of tuberculosis can only be estimated because no accurate data are available from national country programmes from of high tuberculosis endemic countries. The WHO 201
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