• br Introduction Despite the widespread use

  2019-05-10

  

  Introduction Despite the widespread use of bone-targeted agents in the care of patients with bone metastases from prostate and breast cancer, questions regarding the optimal; choice of agent, dose, dosing frequency, and duration of therapy remain unanswered [1–6]. Our research group is interested

• Landiolol is an ultra short

  2019-05-10

  

  Landiolol is an ultra-short-acting, β1-superselective, titration intravenous β-adrenergic blocker that is rapidly metabolized to inactive forms, and has relatively smaller negative inotropic effects on the cardiac output [11]. Landiolol is more effective for controlling rapid over here rate than di

• According to the Disease Early Warning System infectious dis

  2019-05-10

  

  According to the Disease Early Warning System, infectious diseases were widespread during the flood, including cases of cholera, malaria, and polio, consistent with exposure of displaced people to disease orexin antagonist and conditions of poor hygiene in camps and shelters. Disruption to the mana

• The effectiveness of the intervention varied across district

  2019-05-10

  

  The effectiveness of the intervention varied across districts, with the proportion of infections averted inversely related to pre-intervention consistent condom use (appendix). Understandably, for districts in which previous interventions had already led to high consistent condom use among high-risk

• Performance based financing often highlighted in Rwanda s st

  2019-05-10

  

  Performance-based financing, often highlighted in Rwanda\'s story, has had mixed results when applied elsewhere, partly because of breakdowns in execution. For example, the failure of the performance-based financing initiative in neighbouring Uganda was caused by challenges in setting targets, deliv

• Para Estados Unidos Argentina no ha sido comercialmente rele

  2019-05-10

  

  Para Estados Unidos, Argentina no ha sido comercialmente relevante Pirfenidone pesar de que ocupó el puesto 29 entre sus destinos de exportación, y que las ventas norteamericanas aumentaron más del doble en relación a lo que importó del país latinoamericano. Incluso, casi 85% del total de las export

• En estos trabajos la referencia a

  2019-05-10

  

  En estos trabajos la referencia abscisic acid la obra de Ernesto Laclau es una constante, que a su vez es marginal. Casi todos los estudios lo citan como un antecedente en ese lugar común que se transformó el referir a la polisemia del concepto y es difícil considerar un estado de la cuestión sin su

• With the availability of vaccines screen and treat approache

  2019-05-10

  

  With the availability of vaccines, screen-and-treat approaches, and effective drugs to treat hepatitis C virus, , and HIV infections, the question is no longer limited to what to do but now extends to how to implement. The expanding focus from basic research, drug development, and clinical trials th

• Although the NCCN IPI is a promising simple scale based

  2019-05-10

  

  Although the NCCN-IPI is a promising simple scale based on conventional clinical factors, its usefulness remains controversial [6,7]. It should be evaluated in populations of different regions and ethnicities before adopting it for routine clinical use. Conflict of interest Report At presenta

• In this case report we described a rare case of

  2019-05-09

  

  In this case report, we described a rare case of tumor lysis syndrome associated with the FOLFOX regimen and further stress the importance of additional prophylaxis for the huge tumor burden. Our patient\'s hyperammonemia may be due to cardiogenic shock, post cardio-pulmonary-cerebral resuscitation

• In the past decade preclinical studies

  2019-05-09

  

  In the past decade, preclinical studies have addressed the putative role of non-coding RNAs in tumorigenesis, metastasis and therapy response in osteotropic cancers. Besides long non-coding RNAs, microRNAs (miRs) represent a class of small non-coding RNAs, (18–25 nucleotides long), that regulate pro

• Early repolarization ER is characterized by elevation of

  2019-05-09

  

  Early repolarization (ER) is characterized by elevation of the QRS-ST junction (J point) and QRS notching or slurring (J wave) in multiple leads, especially the inferior and/or left precordial leads. Although this finding has been considered to be a benign ECG manifestation, Haïssaguerre et al repor

• Baseline WBC count and baseline measures

  2019-05-09

  

  Baseline WBC count and baseline measures of hepatic and renal function for responders and nonresponders are shown in Table 1. No relationship was evident between responders to decitabine or treatment choice and baseline WBC counts, or between responders and baseline measures of hepatic function (ALT

• br Discussion Our results confirm that germline

  2019-05-09

  

  Discussion Our results confirm that germline variations in the TPMT gene are associated with treatment outcome in children with ALL [5]. The ability of TPMT to catalyze S-methylation and inactivate 6-mercaptopurine makes it a major determinant of 6-mercaptopurine toxicity. Furthermore, reduced TP

• With centralisation timely and efficient distribution networ

  2019-05-08

  

  With centralisation, timely and efficient distribution networks are key. However, mature blood distribution networks are yet to be established in most developing countries. For example, blood donated in Malawi\'s capital Lilongwe is sent to Blantyre (360 km away) for testing at MBTS before it is tra

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