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br Methods The Spanish GEM MAS trial lasted from March
2019-06-06
Methods The Spanish GEM05MAS65 trial lasted from March, 2006 to October, 2008 and included 260 patients from 63 Spanish centers. At study entry, every patient was aged 65 years or older and had newly diagnosed, untreated, symptomatic, measurable MM. These patients had received a homogeneous induc
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br In an age when
2019-06-06
In an age when everything from sparrows to toilets has its own international day (March 20 and November 19, respectively, in case you were wondering), it\'s perhaps no surprise that the scholarly publishing SBI-0206965 Supplier has got in on the act. This week is . Organised by representatives f
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br Diagnostic criteria Brugada syndrome is definitively diag
2019-06-06
Diagnostic criteria Brugada syndrome is definitively diagnosed when a type-1 ST-segment elevation is observed in at least 1 right precordial lead (V1 and V2) [23], placed in a standard or a superior position (up to the second intercostal space) (Fig. 1C) [24,25], in the presence or absence of a s
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In this case report we described
2019-06-06
In this case report, we described a rare case of tumor lysis syndrome associated with the FOLFOX regimen and further stress the importance of additional prophylaxis for the huge tumor burden. Our patient\'s hyperammonemia may be due to cardiogenic shock, post cardio-pulmonary-cerebral resuscitation
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The authors of the NCCN non small
2019-06-06
The authors of the NCCN non-small cell lung cancer guidelines provide the most guidance about radiotherapy dosing for painful bone metastases of any of the primary sites evaluated [39]. Bone metastases due to non-small cell lung cancer are separated into those “with soft tissue mass” versus those “w
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The requirements for establishing this arrhythmia are as fol
2019-06-06
The requirements for establishing this arrhythmia are as follows: (1) a slow pathway (or maybe a fast pathway) should not have retrograde conduction; and (2) the refractory SEA0400 of the distal common pathway must be shorter than the difference in the conduction times over the fast and slow pathwa
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A substantial body of evidence linking inflammation
2019-06-05
A substantial body of evidence linking inflammation to the pathophysiology of a broad spectrum of cardiovascular diseases, including coronary artery disease, diabetes mellitus, and hypertension, has been developed [8–11]. Similarly, the hypothesis that inflammatory processes are involved in the path
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br Materials methods br Results br Discussion The
2019-06-05
Materials-methods Results Discussion The general statement that can be concluded from the studies comparing the utility of 18F–NaF PET or PET/CT with 99mTc- MDP whole body bone scintigraphy is that 18F–NaF PET/CT generally has a higher sensitivity and specificity than bone scan. Higher upta
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Hill and colleagues estimate that globally about
2019-06-01
Hill and colleagues\' estimate that, globally, about 1·5 million (95% CI 1·2–1·8) children aged 5–14 years died in 2010. This finding is somewhat higher than the total estimated by the UN of 1·3 million, although the UN estimate is within the investigators\' CI. However, their estimate is 87% higher
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tranylcypromine En otra rbita George Y dice
2019-06-01
En otra órbita, George Yúdice establece una doble genealogía refiriéndose al testimonio que se realiza tranylcypromine partir de la información que proporciona un sujeto subalterno a un escritor o a un intelectual. Yúdice se refiere aquí a la pedagogía de los oprimidos de Paulo Freire y a la Teolog
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br The UN high level Summit for Refugees
2019-06-01
The 2016 UN high-level Summit for Refugees and Migrants in New York (NY, USA) provided a historic opportunity to engage world leaders in responding to the health dimensions of mass migration. Despite the magnitude of the phenomenon and its potential for changing global as well as national health p
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More recently primary tumor driven generation of
2019-06-01
More recently, primary tumor driven generation of a bone pre-metastatic niche was observed in a mouse model of estrogen receptor-negative breast cancer metastasis. Specifically, lysyl oxidase (LOX) secreted into the circulation from hypoxic primary breast tumors disrupted bone homeostasis, thereby i
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Heat shock facilitates the folding of
2019-06-01
Heat shock facilitates the folding of various proteins as mediated by the HSP family and can stabilize mutant proteins. HS has been reported to facilitate maturation of WT-HERG as well as mutant HERG by activating the HSF family [15]. HSF-1, 2, and 4 were reported to be expressed in humans. HSF-1 is
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palmitic acid The increasing burden of NCDs poses an
2019-06-01
The increasing burden of NCDs poses an enormous threat to populations and health systems across the globe. The Sustainable Development Goals represent an important opportunity to integrate efforts to reduce the burden of NCDs and promote sustainable development. The recent identification of NCDs as
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Although Afnan Holmes and colleagues report covers
2019-06-01
Although Afnan-Holmes and colleagues\' report covers substantial ground, several issues remain unexamined. For example, why have facility delivery rates in the country stagnated at roughly 50% over the past decade? Although enhancement of women\'s agency in making health-care decisions is necessary,
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